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OBO ID: CHEBI:3749
Term Name: clofazimine Search Ontology:
Synonyms:
  • (4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine
  • 3-(p-chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
  • 3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
  • clofazimina
  • clofazimine
  • clofaziminum
  • N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
  • N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
Definition: 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
References:
  • Beilstein:8168151
  • CAS:2030-63-9
  • DrugBank:DB00845
  • KEGG:C06915
  • KEGG:D00278
  • LINCS:LSM-5669
  • PMID:17210775
  • PMID:3279207
  • Patent:US2948726
Ontology: Chebi
PHENOTYPE No data available