OBO ID: CHEBI:31588

Term Name:	fabesetron		Search Ontology:
Synonyms:	(+)-(R)-8,9-dihydro-10-methyl-7-((5-methylimidazol-4-yl)methyl)pyrido[1,2-a]indol-6(7H)-one (7R)-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-8,9-dihydropyrido[1,2-a]indol-6(7H)-one fabesetron fabesetronum FK 1052 FK-1052 FK1052
Definition:	An organic heterotricyclic compound that is 8,9-dihydropyrido[1,2-a]indol-6(7H)-one substituted by a (5-methyl-1H-imidazol-4-yl)methyl group at position 7R and a methyl group at position 10. It is a dual 5-HT3 and 5-HT4 receptors antagonist whose clinical development was terminated in phase II. It was being developed for the treatment of chemotherapy-induced emesis and irritable bowel syndrome.
References:	CAS:129300-27-2 PMID:10688616 PMID:11560875 PMID:16079468 PMID:7553979 PMID:7697771 PMID:7697772 PMID:8331576 PMID:8496821 PMID:8944700
Ontology:	ChEBI  ( EBI )