| Term Name: |
doxifluridine |
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Search Ontology:
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| Synonyms: |
- 1-(beta-D-5-desoxyribofuranoxyl)-5-fluoruracil
- 5'-deoxy-5-fluorouridine
- 5'-Dfur
- 5'-dFUrd
- 5-fluoro-5'-deoxyuridine
- doxifluridina
- doxifluridine
- doxifluridinum
- Furtulon
- Ro 21-9738
- Ro 219738
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| Definition: |
A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.
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| References: |
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| Ontology: |
ChEBI
(
EBI
)
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Show first 5 Terms
