OBO ID: CHEBI:31439
Term Name: crotamiton Search Ontology:
Synonyms:
  • crotalgin
  • crotamiton
  • crotamitone
  • crotamitonum
  • crotonyl-N-ethyl-o-toluidine
  • N-ethyl-N-(2-methylphenyl)but-2-enamide
  • N-ethyl-o-crotonotoluidide
Definition: An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.
References:
  • Beilstein:3275497
  • CAS:483-63-6
  • DrugBank:DB00265
  • Drug_Central:744
  • KEGG:D01381
  • LINCS:LSM-3274
  • Patent:GB615137
Ontology: Chebi
PHENOTYPE No data available