OBO ID: CHEBI:27899

Term Name:	cisplatin		Search Ontology:
Synonyms:	(SP-4-2)-diamminedichloridoplatinum (SP-4-2)-diamminedichloroplatinum [PtCl2(NH3)2] Briplatin CDDP cis-[PtCl2(NH3)2] cis-DDP cis-diamminedichloridoplatinum(II) cis-diamminedichloroplatinum cis-Diamminedichloroplatinum(II) cis-diammineplatinum(II) dichloride cis-dichlorodiammineplatinum(II) cis-platin Cismaplat Cisplatin cisplatine cisplatino cisplatinum Lederplatin Neoplatin Peyrone's chloride Peyrone's salt Platamine Platinex Platinol Randa
Definition:	A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
References:	CAS:15663-27-1 DrugBank:DB00515 Gmelin:2519 HMDB:HMDB0014656 KEGG:C06911 KEGG:D00275 MetaCyc:CPD0-1392 MolBase:25 PMID:10883661 PMID:12537968 PMID:12831510 PMID:12935404 PMID:16327988 PMID:18472761 PMID:1855275 PMID:23554447 PMID:23604226 PMID:23651576 PMID:28494534 Patent:DE2318020 Patent:DE2329485 Reaxys:11324567 Wikipedia:Cisplatin
Ontology:	ChEBI  ( EBI )