ZFIN ChEBI: naxagolide

OBO ID: CHEBI:177372

Term Name:	naxagolide		Search Ontology:
Synonyms:	(+)-4-propyl-9-hydroxynaphthoxazine (+)-PHNO (4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol (4aR-trans)-3,4,4a,5,6,10b-hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol dopazinol naxagolida naxagolide naxagolidum nazagolide PHNO
Definition:	An organic heterotricyclic compound that is (4aR,10bR)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazine substituted by propyl and hydroxy groups at positions 4 and 9, respectively. It is a potent dopamine D2-receptor agonist and its hydrochloride salt was under clinical development by Merck & Co as a potential antiparkinsonian agent (now discontinued).
References:	CAS:88058-88-2 Chemspider:51863 PMID:10956195 PMID:11105937 PMID:15646539 PMID:15943487 PMID:1681090 PMID:1840645 PMID:19635669 PMID:2140595 PMID:24325578 PMID:2904649 PMID:3758188 PMID:6433000 PMID:8078498 PMID:8301582
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	organic heterotricyclic compound phenols tertiary amino compound organic heterotricyclic compound phenols tertiary amino compound Show first 5 Terms
has_role:	anticonvulsant antiparkinson drug dopamine agonist anticonvulsant antiparkinson drug dopamine agonist Show first 5 Terms
inverse is_conjugate_acid_of:	naxagolide(1+) naxagolide(1+) Show first 5 Terms
is_conjugate_base_of:	naxagolide(1+) naxagolide(1+) Show first 5 Terms

PHENOTYPE No data available