OBO ID: CHEBI:176501

Term Name:	iFSP1		Search Ontology:
Synonyms:	1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile 1-amino-3-(p-tolyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile iFSP 1 iFSP-1
Definition:	A member of the class of pyridobenzimidazoles that is pyrido[1,2-a]benzimidazole substituted by amino, cyano, 4-methylphenyl, and cyano groups at positions 1, 2, 3 and 4, respectively. It is a potent inhibitor of ferroptosis suppressor protein 1 (FSP1) with EC50 of 103 nM. It induces ferroptosis in GPX4 knockout cells that overexpress FSP1.
References:	CAS:150651-39-1 PMID:31634899 PMID:31634900 PMID:32100402
Ontology:	ChEBI  ( EBI )