OBO ID: CHEBI:168396

Term Name:	mycophenolic acid		Search Ontology:
Synonyms:	(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid acide mycophenolique acido micofenolico acidum mycophenolicum Micofenolico acido Mycophenolate mycophenolic acid Mycophenolsaeure
Definition:	A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.
References:	Beilstein:318158 CAS:24280-93-1 DrugBank:DB01024 Drug_Central:1860 KEGG:D05096 PDBeChem:MOA PMID:11272311 PMID:15470161 PMID:16629948 PMID:16640327 PMID:17482154 PMID:17498396 PMID:18194117 PMID:18611107 PMID:18996104 PMID:19689217 Patent:US4753935 Reaxys:318158 Wikipedia:Mycophenolic_acid
Ontology:	ChEBI  ( EBI )