OBO ID: CHEBI:167314

Term Name:	KOM70144		Search Ontology:
Synonyms:	(R)-5-acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide 5-acetamido-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide 5-N-acetylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide
Definition:	A benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 muM and 5.0 muM, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 muM, respectively).
References:	CAS:1093070-14-4 PMID:18852458 PMID:32428392 PMID:33251371
Ontology:	ChEBI  ( EBI )