ZFIN ChEBI: tigecycline

OBO ID: CHEBI:149836

Term Name:	tigecycline		Search Ontology:
Synonyms:	(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide (4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
Definition:	Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms.
References:	CAS:220620-09-7 DrugBank:DB00560 Drug_Central:2661 KEGG:C12012 KEGG:D01079 PMID:17194827 PMID:17210772 PMID:17220399 PMID:17307973 PMID:17353238 PMID:17353249 Reaxys:8379453
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	tertiary alpha-hydroxy ketone tetracyclines tertiary alpha-hydroxy ketone tetracyclines Show first 5 Terms
has_role:	antibacterial drug antibacterial drug Show first 5 Terms
inverse has_functional_parent:	11a-hydroxytigecycline(1+) 11a-hydroxytigecycline(1+) Show first 5 Terms
inverse is_conjugate_acid_of:	tigecycline(1+) tigecycline(1+) Show first 5 Terms
is_conjugate_base_of:	tigecycline(1+) tigecycline(1+) Show first 5 Terms

PHENOTYPE No data available