OBO ID: CHEBI:144400

Term Name:	dinophysistoxin 1		Search Ontology:
Synonyms:	(2R)-3-[(2S,5R,6R,8S)-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-6'-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl]-1-hydroxybutyl}-8'-hydroxy-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-5 35-Methylokadaic acid Dinophysistoxin-1 DTX 1 DTX-1 DTX1
Definition:	A ketal that is a marine toxin structurally related to okadaic acid. Produced by dinoflagellates it is known to accumulate in shellfish and cause diarrhoeic shellfish poisoning. It is an inhibitor of serine/threonine protein phosphatases 1 (PP1) and PP2A and has been shown to promote cancer cell growth in tumour cell lines and animal models.
References:	CAS:81720-10-7 FooDB:FDB002306 HMDB:HMDB0030442 KEGG:C16870 KNApSAcK:C00044717 PMID:10398517 PMID:17455957 PMID:1905699 PMID:19481560 PMID:23127709 PMID:24394641 PMID:25238672 PMID:25826053 PMID:26426049 PMID:27956244 PMID:28366404 PMID:29491228 PMID:30176657 PMID:30884396 PMID:3564062
Ontology:	ChEBI  ( EBI )