OBO ID: CHEBI:143825
Term Name: ravuconazole Search Ontology:
Synonyms:
  • 4-[2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
  • BMS 207147
  • BMS-20714
  • ER 30346
  • ER-30346
  • ravuconazol
  • ravuconazole
  • ravuconazolum
Definition: A member of the class of triazoles that is 1-butyl-1H-1,2,4-triazole in which the butyl group is substituted at positions 2, 2, and 3 by hydroxy, 2,4-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively (the R,R stereoisomer). It exhibits antifungal activity by inhibition of 14alpha demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCIO4)
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available