OBO ID: CHEBI:142835
Term Name: (R)-DRF053 hydrochloride hydrate Search Ontology:
Synonyms:
  • (2R)-2-({9-isopropyl-6-[3-(pyridin-2-yl)anilino]-9H-purin-2-yl}amino)butan-1-ol hydrochloride hydrate
  • (R)-DRF053.HCl.H2O
  • (R)-DRF053.xHCl.yH2O
  • 2-[[9-(1-methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]- 9H-purin-2-yl]amino]-1-butanol hydrochloride hydrate
Definition: A hydrochloride and hydrate of DRF053, an analogue (and more potent version) of roscovitine - it is 2 fold more potent against cyclin dependent kinase 5 (CDK5) and >150 times more potent against CDK1. Formula C23H27N7O.xHCl.yH2O.
References:
  • Pubchem:329798839
Ontology: Chebi
PHENOTYPE No data available