OBO ID: CHEBI:141063
Term Name: rubimaillin Search Ontology:
Synonyms:
  • methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
  • mollugin
Definition: A benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available