OBO ID: CHEBI:140154
Term Name: cyclosporin A metabolite M17 Search Ontology:
Synonyms:
  • (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23
  • 6-[(2S,3R,4R,6E)-3,8-dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin
  • AM1
  • CsA M17
  • cyclosporin metabolite AM1
  • cyclosporin metabolite M17
  • cyclosporine A metabolite M17
  • cyclosporine metabolite M17
  • M17
  • OL 17
  • OL-17
Definition: A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol. It specifically inhibits growth of renal cells in culture.
References:
Ontology: Chebi
PHENOTYPE No data available