ZFIN ChEBI: GGTI-2133 free base

OBO ID: CHEBI:101257

Term Name:	GGTI-2133 free base		Search Ontology:
Synonyms:	GGTI 2133 free base N-[4-{[(1H-imidazol-4-yl)methyl]amino}-2-(naphthalen-1-yl)benzoyl]-L-leucine
Definition:	An N-acyl-L-amino acid obtained by condensation of the carboxy group of 4-{[(imidazol-4-yl)methyl]amino}-2-(naphthalen-1-yl)benzoic acid with the amino group of L-leucine. An inhibitor of geranylgeranyltransferase type I.
References:	PMID:23335799 PMID:23415632 PMID:23649168 PMID:23744643 PMID:24486886 PMID:25882623 Reaxys:25113814
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	benzamides biaryl imidazoles L-leucine derivative N-acyl-L-amino acid ... Show All 8 Terms benzamides biaryl imidazoles L-leucine derivative N-acyl-L-amino acid naphthalenes secondary amino compound substituted aniline Show first 5 Terms
has_role:	EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor Show first 5 Terms
inverse is_conjugate_acid_of:	GGTI-2133 free base(1+) GGTI-2133 free base(1+) Show first 5 Terms
is_conjugate_base_of:	GGTI-2133 free base(1+) GGTI-2133 free base(1+) Show first 5 Terms

PHENOTYPE No data available