Term Name: esophagus
Synonyms: gullet, oesophagus
Definition: Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).
Ontology: Cell Ontology [UBERON:0001043]

Relationships
is part of: upper digestive tract
has parts: abdominal part of esophagus adventitia of esophagus cervical part of esophagus crop epithelial cell of esophagus epithelium of esophagus esophageal sphincter esophageal taste bud esophagus mucosa esophagus muscle esophagus muscularis mucosa esophagus secretion esophagus skeletal muscle esophagus smooth muscle circular layer esophagus squamous epithelium glandular cell of esophagus lamina propria of esophagus lower esophagus lumen of esophagus mesentery of oesophagus middle part of esophagus muscle layer of esophagus peptonephridium pneumatic duct serosa of esophagus smooth muscle cell of the esophagus smooth muscle of esophagus submocosal esophageal gland submucosa of esophagus thoracic part of esophagus upper esophagus wall of esophagus
is a type of: digestive system element organ subdivision of digestive tract thoracic cavity element