Term Name: | super elongation complex |
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Synonyms: | ELL-EAF complex, ELL-EAF-EBP complex |
Definition: | A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae. |
Ontology: | GO: Cellular Component [GO:0032783] QuickGO AmiGO |