Term Name: | GLI-SUFU complex |
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Synonyms: | |
Definition: | A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. |
Ontology: | GO: Cellular Component [GO:1990788] QuickGO AmiGO |