Term Name: | Dom34-Hbs1 complex |
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Synonyms: | Dom34:Hbs1 complex |
Definition: | A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay. |
Ontology: | GO: Cellular Component [GO:1990533] QuickGO AmiGO |