Term Name: | mitotic checkpoint complex, CDC20-MAD2 subcomplex |
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Synonyms: | CDC20-MAD2 complex |
Definition: | A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20. |
Ontology: | GO: Cellular Component [GO:1990333] QuickGO AmiGO |