Term Name:	STING complex
Synonyms:	stimulator of interferon genes complex
Definition:	A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.
Ontology:	GO: Cellular Component [GO:1990231]    QuickGO    AmiGO