Term Name:	nonsense-mediated decay complex
Synonyms:	Upf complex
Definition:	A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
Ontology:	GO: Cellular Component [GO:0170010]    QuickGO    AmiGO