Term Name:	chromosomal 5-methylcytosine DNA demethylation, oxidation pathway
Synonyms:	epigenetic 5-methylcytosine DNA demethylation, oxidation pathway, epigenetic DNA demethylation, oxidation pathway
Definition:	An epigenetic cytosine DNA demethylation pathway that starts with the enzymatic oxidation of the 5-methylcytosine (5meC) to generate 5-hydroxymethylcytosine (5hmC), which successively converted to 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). A DNA glycosylase (e. g. TDG) recognizes the intermediate bases 5fC and 5caC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair.
Ontology:	GO: Biological Process [GO:0141167]    QuickGO    AmiGO