| Term Name: | target-directed miRNA degradation |
|---|---|
| Synonyms: | target-directed microRNA degradation, TDMD |
| Definition: | The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases. |
| Ontology: | GO: Biological Process [GO:0140958] QuickGO AmiGO |