Term Name: | pore-forming activity |
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Synonyms: | canonical holin activity, holin activity, pinholin activity, pore forming activity |
Definition: | An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death. |
Ontology: | GO: Molecular Function [GO:0140911] QuickGO AmiGO |