Term Name: | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
---|---|
Synonyms: | AP lyase activity, class I AP endonuclease activity, class I DNA-(apurinic or apyrimidinic site) lyase activity, DNA-(apurinic or apyrimidinic site) lyase activity |
Definition: | Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate. |
Ontology: | GO: Molecular Function [GO:0140078] QuickGO AmiGO |