Term Name:	ubiquitin activating enzyme complex
Synonyms:	E1 complex
Definition:	A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
Ontology:	GO: Cellular Component [GO:0120123]    QuickGO    AmiGO