Term Name: | histone H3K18 deacetylase activity, NAD-dependent |
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Synonyms: | NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone H3-K18 deacetylase activity, NAD-dependent histone H3K18 deacetylase activity |
Definition: | Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + NAD+ + H2O = histone H3 L-lysine (position 18) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K18 to NAD, producing nicotinamide. |
Ontology: | GO: Molecular Function [GO:0097372] QuickGO AmiGO |