Term Name: | tetraspanin-enriched microdomain |
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Synonyms: | membrane tetraspanin-enriched microdomain, TEM |
Definition: | A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities. |
Ontology: | GO: Cellular Component [GO:0097197] QuickGO AmiGO |