Term Name:	siRNA-mediated gene silencing by mRNA destabilization
Synonyms:	gene silencing by mRNA cleavage, mRNA cleavage involved in gene silencing by siRNA, mRNA destabilization-mediated gene silencing by siRNA
Definition:	An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
Ontology:	GO: Biological Process [GO:0090625]    QuickGO    AmiGO