Term Name: | BRCA1-A complex |
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Synonyms: | |
Definition: | A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. |
Ontology: | GO: Cellular Component [GO:0070531] QuickGO AmiGO |