Term Name: | nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay |
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Synonyms: | 5'-3' NMD, 5'-3' nonsense-mediated decay, 5'-3' nonsense-mediated mRNA decay, nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay |
Definition: | The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. |
Ontology: | GO: Biological Process [GO:0070479] QuickGO AmiGO |