Term Name: | elongin complex |
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Synonyms: | elongin (SIII) complex, transcription elongation factor SIII complex, transcription factor B (SIII) complex |
Definition: | A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits. |
Ontology: | GO: Cellular Component [GO:0070449] QuickGO AmiGO |