Term Name: | R-loop processing |
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Synonyms: | R-loop disassembly |
Definition: | A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. |
Ontology: | GO: Biological Process [GO:0062176] QuickGO AmiGO |