Term Name: | relaxation of vascular associated smooth muscle |
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Synonyms: | negative regulation of relaxation of vascular smooth muscle, positive regulation of relaxation of vascular smooth muscle, regulation of relaxation of vascular smooth muscle, relaxation of vascular smooth muscle, vascular smooth muscle relaxation |
Definition: | A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. |
Ontology: | GO: Biological Process [GO:0060087] QuickGO AmiGO |