Term Name: | Ku70:Ku80 complex |
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Synonyms: | Ku70:Ku80 heterodimer |
Definition: | Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK. |
Ontology: | GO: Cellular Component [GO:0043564] QuickGO AmiGO |