Term Name: proteasome-mediated ubiquitin-dependent protein catabolic process
Synonyms: proteasomal pathway, proteasomal processing, proteasomal ubiquitin-dependent protein breakdown, proteasomal ubiquitin-dependent protein catabolic process, proteasomal ubiquitin-dependent protein catabolism, proteasomal ubiquitin-dependent protein degradation, proteasome pathway
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Ontology: GO: Biological Process [GO:0043161]    QuickGO    AmiGO

Relationships
is a type of: proteasomal protein catabolic process ubiquitin-dependent protein catabolic process
has subtype: anaphase-promoting complex-dependent catabolic process cytoplasm protein quality control by the ubiquitin-proteasome system mitochondria-associated ubiquitin-dependent protein catabolic process negative regulation of transcription by transcription factor catabolism nuclear protein quality control by the ubiquitin-proteasome system ribosome-associated ubiquitin-dependent protein catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process stress-induced homeostatically regulated protein degradation pathway ubiquitin-dependent protein catabolic process via the C-end degron rule pathway ubiquitin-dependent protein catabolic process via the N-end rule pathway
inverse has_part: endoplasmic reticulum stress-induced pre-emptive quality control
negatively regulated by: negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positively regulated by: positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulated by: regulation of proteasomal ubiquitin-dependent protein catabolic process