Term Name: NADPH oxidase complex
Synonyms: flavocytochrome b558, respiratory-burst oxidase
Definition: A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
Ontology: GO: Cellular Component [GO:0043020]    QuickGO    AmiGO

Relationships
is a type of: oxidoreductase complex plasma membrane protein complex