Term Name: | symbiont-mediated evasion of mRNA degradation by host via mRNA cap methylation |
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Synonyms: | evasion of mRNA degradation by host via mRNA cap methylation, IFIT mRNA restriction evasion by virus, viral mRNA cap methylation |
Definition: | An innate immune response evasion mechanism in which a symbiont methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs. This mechanism of immune evasion is used by viruses. |
Ontology: | GO: Biological Process [GO:0039699] QuickGO AmiGO |