Term Name: | symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity |
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Synonyms: | inhibition of host MAVS by virus, suppression by virus of host MAVS activity, suppression by virus of host mitochondrial antiviral-signaling protein, suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity |
Definition: | A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses. |
Ontology: | GO: Biological Process [GO:0039545] QuickGO AmiGO |