Term Name: | large latent transforming growth factor-beta complex |
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Synonyms: | large latent complex, LLC |
Definition: | A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors. |
Ontology: | GO: Cellular Component [GO:0038045] QuickGO AmiGO |