Term Name: | positive regulation of signal transduction by receptor internalization |
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Synonyms: | positive regulation of signaling pathway by receptor endocytosis |
Definition: | Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms. |
Ontology: | GO: Biological Process [GO:0038010] QuickGO AmiGO |