Term Name: calcitriol biosynthetic process from calciol
Synonyms: 1alpha,25(OH)2D3 biosynthesis, 1alpha,25-dihydroxycholecalciferol biosynthesis, 1alpha,25-dihydroxyvitamin D3 biosynthesis, calcitriol biosynthesis from calciol, vitamin D3 activation
Definition: Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.
Ontology: GO: Biological Process [GO:0036378]    QuickGO    AmiGO

Relationships
has parts: calcidiol 1-monooxygenase activity vitamin D3 25-hydroxylase activity
is a type of: polyol biosynthetic process vitamin D biosynthetic process vitamin D3 metabolic process