Term Name: interstrand cross-link repair
Synonyms: ICL repair
Definition: Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.
Ontology: GO: Biological Process [GO:0036297]    QuickGO    AmiGO

Relationships
has parts: nucleotide-excision repair involved in interstrand cross-link repair
is a type of: DNA repair
has subtype: non-recombinational interstrand cross-link repair recombinational interstrand cross-link repair