Term Name: | Hedgehog signaling complex |
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Synonyms: | Hedgehog signalling complex, HSC |
Definition: | A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila). |
Ontology: | GO: Cellular Component [GO:0035301] QuickGO AmiGO |