Term Name: | CFTR-NHERF-ezrin complex |
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Synonyms: | |
Definition: | A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity. |
Ontology: | GO: Cellular Component [GO:0034662] QuickGO AmiGO |