| Term Name: | CFTR-NHERF-ezrin complex |
|---|---|
| Synonyms: | |
| Definition: | A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity. |
| Ontology: | GO: Cellular Component [GO:0034662] QuickGO AmiGO |