Term Name:	25-hydroxycholesterol 7-alpha-hydroxylase activity
Synonyms:	25-hydroxycholesterol 7alpha-monooxygenase activity, cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase activity
Definition:	Catalysis of the reactions: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts (25R)-cholest-5-ene-3beta,26-diol to (25R)-cholest-5-en-3beta,7alpha,26-triol.
Ontology:	GO: Molecular Function [GO:0033783]    QuickGO    AmiGO