| Term Name: | TSC1-TSC2 complex |
|---|---|
| Synonyms: | tuberin-hamartin complex, tuberous sclerosis complex |
| Definition: | A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. |
| Ontology: | GO: Cellular Component [GO:0033596] QuickGO AmiGO |