Term Name: leptin-mediated signaling pathway
Synonyms: adipocytokine signaling pathway, leptin-mediated signalling pathway
Definition: The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
Ontology: GO: Biological Process [GO:0033210]    QuickGO    AmiGO

Relationships
is part of: cellular response to leptin stimulus
has parts: leptin receptor activity
is a type of: cytokine-mediated signaling pathway
has subtype: negative regulation of appetite by leptin-mediated signaling pathway